Register for day one
9:00 Registration and networking
10:00 Welcome and conference introduction
David Ramsden, Chief Executive, Cystic Fibrosis Trust
10:05 Setting the scene for day one
Dr Janet Allen, Director of Strategic Innovation, Cystic Fibrosis Trust
10:10 Session one: Development of new therapies for cystic fibrosis
Chair: Dr Mike Gray, Newcastle University
New therapies for cystic fibrosis are under development, and some of these therapies may improve the way existing precision medicines work or cause them to work in a novel and different way. In this session we'll hear from two companies with different approaches, including therapies that may work for anyone irrespective of their genotype. The session will end with a brief Q&A.
10:15 Replace instead of repair – novel therapeutics for all CF patients
Professor Martin Gosling PhD, Chief Scientific Officer, Enterprise Therapeutics
10:40 Access and the Unmet Need: Novel CFTR Modulator Combinations are Coming
Dr Marija Zecevic, Proteostasis
11:10 Coffee and networking (Exhibition area)
11:30 - Session two: Innovative ways to reduce burden of care
Digital health technology has the potential to improve the length and quality of life for people with cystic fibrosis. Our speakers will provide updates on research funded and supported by the Trust, including the feasibility of home monitoring in children, to applying new knowledge gained from analyzing the data generated from home monitoring.
Four short presentations from:
- SmartCareCF: Andres Floto (Royal Papworth Hospital) and Sammie Read
- CLIMB-CF: Professor Jane Davies and Dr Claire Edmondson (Imperial College London/Royal Brompton Hospital), and Uisdean McKenzie.
- Predicting pulmonary exacerbations: John Winn (Microsoft Research Institute, Cambridge)
- Next steps, Project Breathe: Kirsty Hill (Magic Bullet) and Mark Edwards.
An interactive panel discussion will follow.
13:00 Conference lunch
Meet the sponsors’, networking & poster viewing (Exhibition Area)
14:15 Session three: A showcase of Cystic Fibrosis Trust-funded research
Discover which problems Trust-funded researchers are addressing, how they’re doing it and how the answers they discover could make a difference to people living with cystic fibrosis in the future. This will be a whistle-stop tour of some of the latest three research programmes that are due to start in this October.
Talk 1: Advances in video imaging of cilia motility with applications in CF, Professor Pietro Cicuta, University of Cambridge
Talk 2: Exploring a new approach to tackling fungal infections, Dr Darius Armstrong-James, Imperial College London
Talk 3: Why does Pseudomonas like the CF lung? Dr Martin Welch, University of Cambridge
Talk 4: CF syndicate in Antimicrobial Resistance, Medicines Discovery Catapult, Jessica Lee and Dr Paula Sommer
Q&A panel discussion
15:15 Session four: Personalised medicine
- Plenary - Dr Lisa Strug, Sick Kids, Toronto
- First UK CF Innovation Hub based at the University of Cambridge, Professor Andres Floto
Hear how advances in our understanding of CF will allow us to tailor care and treatments to each person. We know that CF varies in how it appears in different individuals and in how responses to treatments can vary. Some of these differences are down to variations in our genetic make-up. In this session we’ll hear how genetic and machine learning research can help us understand more and how the CF community can help.
Q&A panel discussion
16:15 Coffee & networking
16:45 CF's Got Talent!
Chaired by Cystic Fibrosis Trust supporter, Roger Black MBE, this unique event is an opportunity for our early-career researchers to present their work in a jargon-free way to people with CF and their families.
18:15 Networking drinks reception